Testosterone therapy
Androgens, gonadotropins, and SERMs
The base compounds of testosterone therapy — plus the fertility-preservation and hormone-restoring agents that pair with it.
Androgen · FDA-approved
Testosterone cypionate
The most-prescribed injectable testosterone ester in the United States. Weekly to twice-weekly dosing, decades of clinical use.
Androgen · FDA-approved
Testosterone enanthate
Testosterone cypionate's close chemical cousin — nearly identical pharmacokinetics, available as Xyosted (SubQ auto-injector) and Delatestryl.
Gonadotropin · Fertility
Human chorionic gonadotropin (hCG)
Preserves testicular function and fertility during testosterone therapy. Regulatory landscape shifted after the 2020 FDA biologics reclassification.
SERM · Off-label
Enclomiphene
An oral selective estrogen receptor modulator that raises endogenous testosterone. Denied FDA approval in 2015; still compounded off-label.
Aromatase inhibitor · FDA-approved
Anastrozole
An oral aromatase inhibitor originally approved for breast cancer. Prescribed off-label at micro-doses only when TRT produces symptomatic, lab-confirmed hyperestrogenemia — not as a default TRT add-on.
About this library. This library exists to help patients, prospective patients, and curious readers understand the compounds discussed in testosterone and hormone medicine. Entries cite peer-reviewed sources, FDA documents, and regulatory notices, and are written for a patient audience. Some entries cover compounds Contin-U physicians may prescribe following clinical evaluation; others cover compounds Contin-U does not currently dispense and are provided for educational reference only. This library is not medical advice and does not create a doctor-patient relationship. Always consult a licensed healthcare provider before starting or changing any therapy.